Pod Mod Electronic Cigarettes

E-cigarettes that are not reusable may contribute to the problem of electronic waste. While the data on health effects of conventional tobacco are extensive, the data on e-cigarettes and vaping devices are less established due to their recent entry to the market (Tsai et al., 2020; Bozier et al., 2020). In บุหรี่ไฟฟ้ารุ่นไหนดี , research in this area is impeded by the rapid evolution of vaping devices.


Of note, we did not observe any overt behavioral changes – we closely observe the mice both during and after exposures and make notes regarding grouping, fur, and activity level – none of which were changed by the different vaping exposures. We have added the lack of dedicated behavioral and psychological evaluations as a limitation of this work and as an opportunity for discovery in future studies . Contrary to our initial expectations, we did not find significant changes in autonomic tone or pulmonary function with daily, long-term JUUL aerosol exposure.

There is concern that children may progress from vaping to smoking. Adolescents are likely to underestimate nicotine’s addictiveness. Vulnerability to the brain-modifying effects of nicotine, along with youthful experimentation with e-cigarettes, could lead to a lifelong addiction. A long-term nicotine addiction from using a vape may result in using other tobacco products. The majority of addiction to nicotine starts during youth and young adulthood.

Daily JUUL inhalation for 3 months is associated with neuroinflammation

It is well established that high concentrations of nicotine inhalation are toxic to the human body in a variety of ways (Mishra et al., 2015). JUUL pods have been found to have the highest nicotine concentration of any of the other cartomizer style e-cigarette or refill fluids (Omaiye et al., 2019). Previous studies utilizing continuous systemic delivery of nicotine via implanted pumps concluded that nicotine did not contribute to the development of neuroinflammation.


E-cigarettes cannot be considered safe because there is no safe level for carcinogens. Due to their similarity to traditional cigarettes, e-cigarettes could play a valuable role in tobacco harm reduction. However, the public health community remains divided concerning the appropriateness of endorsing a device whose safety and efficacy for smoking cessation remain unclear.

However, nicotine levels are not the same in all types of e-cigarettes, and sometimes product labels do not list the true nicotine content. Pod mods are a type of electronic cigarette used to vape nicotine through a mouthpiece connected to the body of the device by magnets. These devices are a newer generation of e-cigarettes that are often marketed to a younger crowd that do not wish to attract attention gained through regular e-cigarettes or traditional tobacco-burning cigarettes. Pod mods contain a disposable cartridge and have coils that cannot be removed or changed.

But we absolutely agree that more work is needed to fully define the impact of e-cigarette use at the protein, cellular, and organ level. To obtain the most broad and detailed data possible, we assessed gene transcription across the lung via RNAseq . We have added these RNAseq data, with relevant additions to the Abstract, Methods, Results and Discussion sections.

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