Pod Mod Electronic Cigarettes

E-cigarettes that are not reusable may contribute to the problem of electronic waste. While the data on health effects of conventional tobacco are extensive, the data on e-cigarettes and vaping devices are less established due to their recent entry to the market (Tsai et al., 2020; Bozier et al., 2020). In บุหรี่ไฟฟ้ารุ่นไหนดี , research in this area is impeded by the rapid evolution of vaping devices.

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Of note, we did not observe any overt behavioral changes – we closely observe the mice both during and after exposures and make notes regarding grouping, fur, and activity level – none of which were changed by the different vaping exposures. We have added the lack of dedicated behavioral and psychological evaluations as a limitation of this work and as an opportunity for discovery in future studies . Contrary to our initial expectations, we did not find significant changes in autonomic tone or pulmonary function with daily, long-term JUUL aerosol exposure.

There is concern that children may progress from vaping to smoking. Adolescents are likely to underestimate nicotine’s addictiveness. Vulnerability to the brain-modifying effects of nicotine, along with youthful experimentation with e-cigarettes, could lead to a lifelong addiction. A long-term nicotine addiction from using a vape may result in using other tobacco products. The majority of addiction to nicotine starts during youth and young adulthood.

Daily JUUL inhalation for 3 months is associated with neuroinflammation

It is well established that high concentrations of nicotine inhalation are toxic to the human body in a variety of ways (Mishra et al., 2015). JUUL pods have been found to have the highest nicotine concentration of any of the other cartomizer style e-cigarette or refill fluids (Omaiye et al., 2019). Previous studies utilizing continuous systemic delivery of nicotine via implanted pumps concluded that nicotine did not contribute to the development of neuroinflammation.

Health

E-cigarettes cannot be considered safe because there is no safe level for carcinogens. Due to their similarity to traditional cigarettes, e-cigarettes could play a valuable role in tobacco harm reduction. However, the public health community remains divided concerning the appropriateness of endorsing a device whose safety and efficacy for smoking cessation remain unclear.

However, nicotine levels are not the same in all types of e-cigarettes, and sometimes product labels do not list the true nicotine content. Pod mods are a type of electronic cigarette used to vape nicotine through a mouthpiece connected to the body of the device by magnets. These devices are a newer generation of e-cigarettes that are often marketed to a younger crowd that do not wish to attract attention gained through regular e-cigarettes or traditional tobacco-burning cigarettes. Pod mods contain a disposable cartridge and have coils that cannot be removed or changed.

But we absolutely agree that more work is needed to fully define the impact of e-cigarette use at the protein, cellular, and organ level. To obtain the most broad and detailed data possible, we assessed gene transcription across the lung via RNAseq . We have added these RNAseq data, with relevant additions to the Abstract, Methods, Results and Discussion sections.

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